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Examination of re-excision specimens of completely excised melanomas
The Dutch melanoma guideline advises to examine one central block of the re-excision scar in case of a complete primary excision. To increase the evidence for this recommendation, de Waal and collaegues re-evaluated how often residual melanoma was found in re-excision specimens of a large series of completely excised melanomas. They found that in only 0.5% of cases residual melanoma was detected. ...
Conditional survival for long-term colorectal cancer survivors
This study shows that the prognosis for colorectal cancer survivors improves with each additional year survived, with the largest improvements in the first years after diagnosis. Although colon cancer patients have a better prognosis compared to rectal cancer patients, the difference in conditional 5-year relative survival between colon and rectal cancer disappeared for all patients, except for st...
RCHOP14 versus RCHOP21: symptoms and quality of life:
The increasing number of longer living patients with diffuse large B-cell lymphoma (DLBCL) and serious side effects of treatment, urged Simone Oerlemans (IKNL) and colleagues to study the health-related quality of life (HRQoL) and persistent (treatment-related) symptoms among these patients after different treatment modalities. Patients with DLBCL treated according to the schedule (R-) CHOP14 show...
Patterns of metachronous metastases after treatment of colorectal cancer
The risk of the occurrence of metachronous metastases after treatment of colon and rectal cancer depends on various factors. In addition, there is variation in time to diagnosis and location of metastases. According to dr. Yvette van Gestel (IKNL) and colleagues more insight into these patterns are useful to predict the risk of metachronous metastases,to realize tailor-made care during follow-up a...
Impact of mitotic activity on the staging of thin melanoma
In the transition from the sixth to the seventh edition of the American Joint Committee on Cancer (AJCC) melanoma staging system, mitotic activity was incorporated, while Clark level of invasion was abandoned. Therefore, de Waal and collaegues investigated the effect of this change on the pathological tumour (pT)1 substaging of primary cutaneous melanomas and the possible clinical implications. Th...
More anxiety and depression among lymphoma patients compared to norm
Survival for patients with Hodgkin Lymphoma (HL) and Diffuse Large B-Cell Lymphoma (DLBCL) has improved dramatically over the past decades. As lymphoma patients survive longer, they often face long-term effects caused by their treatment, such as treatment-induced secondary tumors and cardiovascular disease.
Survivorship Care Plans for Primary Care Physician support communication
Supplying Survivorship Care Plans (SCPs) to Primary Care Physician (PCPs) is suggested to be a useful approach to inform the PCP and facilitate communication. Dr. Nicole Ezendam and colleagues showed in a randomized controlled trial that PCPs wish for a SCP and that providing a SCP improves communication with the medical specialist. They also showed that the SCP should be concise and focused on PC...
Chemotherapy-induced peripheral neuropathy & quality of life
According to a systematic review performed by Floortje Mols and colleagues of Tilburg University, the Comprehensive Cancer Center Netherlands and Maxima Medical Center Veldhoven, chemotherapy-induced peripheral neuropathy (CIPN) is likely to have a negative association with quality of life (QOL).
Colorectal signet-ring cell carcinoma is a poor prognostic factor
Signet-ring cell carcinoma (SRCC) is a rare form of colorectal cancer (CRC) and is associated with a poor prognosis. However, whether that outcome is relevant for both colon and rectal sites remains unclear. Likewise, little is known about the efficacy of adjuvant therapy in SRCC. Research from dr. Niek Hugen (Radboudumc) in collaboration with researchers of the Netherlands Cancer Registry on more...
Women with low health literacy are less satisfied with information
Women with low health literacy report that they receive less information about medical tests and they are less satisfied with the information about their disease, treatment and care, irrespective of their educational level. Mariette Verkissen, Nicole Ezendam, Olga Husson and others performed a survey study among 275 women with ovarian tumors.
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