standaard archief
Improved survival with adjuvant chemoradiation after gastric resection 10-11-2014 Patients with stomach cancer undergoing adjuvant chemoradiotherapy after a R1-resection have a better chance to survive than patients who were given no additional therapy after surgery. Research by JurriŽn Stiekema (NKI-AVL) and colleagues shows that adjuvant chemoradiotherapy is an independent prognostic factor for increasing overall survival of these patients. The results of this study were rece... Read further 
Improved survival of stage IV NSCLC due to increased use of chemo 10-11-2014 Due to increased use of chemotherapy in patients with stage IV non-small cell lung cancer (NSCLC), i.e. from 30% in 2001 to 48% in 2012, median survival improved with 3 weeks to 21 weeks in 2010-2012. Several meta-analyses have shown that chemotherapy in addition to best supportive care improves survival in this group of patients, but limited data were available on the use and effects in clinical ... Read further 
More attention needed for individual patient information 10-11-2014 The provision of information to patients with cancer is not optimal. The reason may be that the information provided by doctors and other caregivers is not adapted to the mental health status of cancer patients or that the information is 'insufficient' for the patient. This may result in anxious and depressive symptoms and complaints by patients, according to research of Nienke Beekers (IKNL) and ... Read further 
10 weeks to live: Survival of patients with metastatic pancreatic cancer 10-11-2014 About 80 percent of the patients with pancreatic cancer is diagnosed with locally advanced or metastatic disease and does not qualify for surgical treatment. Furthermore, the majority of patients who are treated with surgery eventually relapses and develops local recurrence of distant metastases. Population-based data on treatment and outcome of metastatic pancreatic cancer are scarce. We conducte... Read further 
(Non-)tumor-related factors associated with esophageal cancer survival 10-11-2014 This study by P. Bus and colleagues showed that both tumor-related (negative lymph nodes and histology) and non-tumor-related factors (surgery, neo-adjuvant therapy, and gender) are associated with survival in esophageal cancer patients. This findings are relevant for clinical decision making. Read further 
More studies quality of life in chronic lymphocytic leukemia needed 10-11-2014 More studies are needed regarding the effects of medical treatment on the quality of life of patients with chronic lymphocytic leukemia / small lymphatic lymphoma. Research by Esther van den Broek (IKNL) and colleagues shows that treatment of these patients leads to a significantly worse quality of life and to large, clinically important differences in relation to patients under active surveillanc... Read further 
Impact BCC and PCC of the skin on health care and society increases 10-11-2014 The incidence of cancer of the keratinocytes (BCC: basal cell carcinoma and PCC: squamous cell carcinoma) has doubled in the Netherlands between 1989-1993 and 2004-2008. As a result, more and more patients have to cope with functional limitations for an extended period of time. More patiŽnts also have to deal with years of life lost. These outcomes confirm that this type of cancer is a major burde... Read further 
Impact of hospital volume on breast cancer outcome in the Netherlands 10-11-2014 The number of breast cancer surgeries that hospitals perform each year, doesnít play a significant role on the chance for breast cancer patients to be cured in the Netherlands. This finding is published by Sabine Siesling (IKNL) and colleagues in Breast Cancer Research and Treatment. The research was conducted in collaboration with the Association of General Hospitals in the Netherlands and medica... Read further 
Colorectal cancer: guidelines-based diagnostic process takes time 10-11-2014 Today, Dutch clinicians face a major challenge to combine the care needs of an aging colorectal cancer population with the introduction of a population-based CRC screening from autumn 2013 onwards. When caseload rises, time intervals until treatment are likely to increase as well. Longer time intervals may provoke more psychological distress and dissatisfaction in patients. Furthermore, more patie... Read further 
Centralization of Esophagectomy: How Far Should We Go? 15-09-2014 This study was designed to define a statistically sound and clinically meaningful cutoff point for annual hospital volume for esophagectomy. Higher hospital volumes are associated with improved outcomes after esophagectomy. However, reported optimal volumes in literature vary, and minimal volume standards in different countries show considerable variation. So far, there has been no research on the... Read further 
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